This is an uncountable noun, designating a general feeling of being worried or unhappy, and having something wrong, for which you don't know some exact symptoms or reasons.
- There is no easy short-term solution to Britain's chronic economic ______.
- He complained of depression, headaches and ______.
- The latest crime figures are merely symptomatic of a wider ______ in society.
- economic/financial/social ______.
- a serious ______ among the employees.
- a general ______ within society.
- One year after the crash the markets remain mired in a deep ______.
- ______ is a state in which there is something wrong with a society or group, for which there does not seem to be a quick or easy solution.
- ______ is a state in which people feel dissatisfied or unhappy but feel unable to change, usually because they do not know what is wrong.
- a feeling of unease or depression.
- a mild sickness, not symptomatic of any disease or ailment.
- a complex of problems affecting a country, economy, etc.
- the problems affecting a particular situation or group of people that are difficult to explain or identity.
- a general feeling of being sick, unhappy, or not satisfied, without signs of any particular problem (=unease).
- a general problem that is difficult to describe in an exact way.
- a general feeling that you are slightly ill or not happy in your life.
- A vague feeling of bodily discomfort, as at the beginning of an illness.
- A general sense of depression or unease.
- a general feeling of being worried, unhappy, or not satisfied.
(1a) a feeling that you are slightly sick, although you cannot say what exactly is wrong.
- a situation in which a society or organization is not operating effectively.
... Cobuild, Collins, OALD, LDOCE, The American Heritage, Macmillan