Dic: a general feeling of worried, unhappy, something wrong

This is an uncountable noun, designating a general feeling of being worried or unhappy, and having something wrong, for which you don't know some exact symptoms or reasons.

• There is no easy short-term solution to Britain's chronic economic ______.
• He complained of depression, headaches and ______.
• The latest crime figures are merely symptomatic of a wider ______ in society.
• economic/financial/social ______.
• a serious ______ among the employees.
• a general ______ within society.
• One year after the crash the markets remain mired in a deep ______.

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1. ______ is a state in which there is something wrong with a society or group, for which there does not seem to be a quick or easy solution. 
2. ______ is a state in which people feel dissatisfied or unhappy but feel unable to change, usually because they do not know what is wrong.

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1. a feeling of unease or depression.
2. a mild sickness, not symptomatic of any disease or ailment.
3. a complex of problems affecting a country, economy, etc.

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1. the problems affecting a particular situation or group of people that are difficult to explain or identity.
2. a general feeling of being sick, unhappy, or not satisfied, without signs of any particular problem (=unease).

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1. a general problem that is difficult to describe in an exact way.
2. a general feeling that you are slightly ill or not happy in your life.

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1. A vague feeling of bodily discomfort, as at the beginning of an illness.
2. A general sense of depression or unease.

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1. a general feeling of being worried, unhappy, or not satisfied.
   (1a) a feeling that you are slightly sick, although you cannot say what exactly is wrong.
2. a situation in which a society or organization is not operating effectively.

... Cobuild, Collins, OALD, LDOCE, The American Heritage, Macmillan