Apraxia (praxis: Greek for an act, work, or deed) is a neurological disorder characterized by loss of the ability to execute or carry out learned purposeful movements, despite having the desire to and the physical ability to perform the movements.
Overview
Apraxia is a disorder of motor planning which may be acquired or developmental, but may not be caused by incoordination, sensory loss, or failure to comprehend simple commands. It is assumed that when performing an action, the motor engram or “space-time plan' has to be conveyed from the left parietal lobe via association fibers to the 'Central region” according to Liepmann (1920); this includes the pre-central and post-central gyri, the middle and superior frontal gyri and their underlying white matter tracts. The Central region affects action through the primary motor cortex. Many studies have confirmed that the left hemisphere has dominance in praxis (Basso et al., 1980, De Renzi et al., 1980,1982). As apraxia is tested through the use of various pantomimes, it has been found in about 50% of the patients with left hemisphere damage and only less than 10% with right hemisphere damage. Apraxia can also be found in diseases of the basal ganglia, including Parkinson's disease, progressive supranuclear palsy and Huntington’s disease and in isolated lesions of the basal ganglia. (중략)
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