in one's (or its) prime: Fig. at one's or its peak or best time. 
- The building was in its prime back in the Fifties, but it has not been well maintained.
 - I could work long hours when I was in my prime.
 
in the prime of life: Fig. in the best and most productive and healthy period of life. 
- The good health of one's youth can carry over into the prime of life.
 - He was struck down by a heart attack in the prime of life.
 
past someone's (or something's) prime: Fig. beyond the most useful or productive period.
- Joan was a wonderful singer, but she's past her prime now.
 - This old car's past its prime. I'll need to get a new one.
 

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